Animal Sciences/Biology/Integrative Biology 231

Biology of Reproduction

Spring 2004 Syllabus[1]

 

 


Instructors:

Darrel J. Kesler, Ph.D.[2]

106 ASL

333-2902

djkesler@uiuc.edu

 

David J. Miller, Ph.D

328 ASL

333-3408

djmille@uiuc.edu

 

Walter L. Hurley, Ph.D

430 ASL

333-1327

wlhurley@uiuc.edu

 

Lectures:

9:00-9:50 M,W,F

150 Animal Sciences Laboratory (ASL)

 

 

Description:   A study of the basic principles of reproduction, lactation, growth, and hormone

regulation of domestic and non-domestic animals as well as humans, including biotechnological methods of reproductive control, performance enhancement, and disease control.

 

 

Specifics:       Prerequisites–Sophomore standing; Biology 104 or one introductory level biology course.


                The course is required for Animal Sciences majors,

                fulfills science credit for students applying to medical, veterinary, or other professional schools, and

                is general education certified for natural sciences.

This course is appropriate for all students, regardless of major.

 

 

Teaching Philosophy:           The primary goal of an undergraduate education is to educate students to function in their future and to adapt to change.  Therefore, I believe we must go beyond teaching sheer memorization and must teach students to become skillful in the thought process.  It is my goal that students learn the ability to integrate and synthesize knowledge and formulate conclusions with their new knowledge.  Therefore, I challenge students to critically and creatively think, apply and use information, analyze issues and ideas, and solve problems.

 

 

Course Objectives:   At the conclusion of the semester, it is my objective that, in addition to having an excellent understanding of reproductive biology and reproductive technologies, you will be able to:

           explain reproductive biology and contraception to others,

                diagnose reproductive dysfunctions and diseases and propose therapeutic solutions,

                use the scientific method,

                understand, objectively interpret, and explain to others new reproductive information and technology as it becomes available, and

                think at a higher level:  integrate and synthesize knowledge, formulate conclusions, critically evaluate issues, and creatively solve problems.

 

Academic Challenges:

 

Lecture Exams (Thinking Exercises; 120 points each)[3],[4]

4

480

Lactation Exam

1

65

Comprehensive Final (Thinking Exercise)[5] (120 points)

1

120

In-class Quizzes (20 points each)[6]

5

80

On-line Quizzes (10 points each)

5

50

Thinking Activities (15 points each)

5

75

Laboratory

 

250

 

Grades:          90-100=A; 80-89=B; 70-79=C; 60-70=D; <60=F

                The grade scale is firm–this is not a curve nor will any “curve” be applied.  The above percentages give you a goal–failing to reach that goal will affect your grade.

                Plus and minus grades will be used only for borderline cases and will not exceed one percentage point (i.e., students with 89-91% may receive an A- or B+).

                Grades will be maintained in Campus GradeBook (http://www.uiuc.edu/ccso/gradebook/).  Please check it routinely for accuracy.

                An optional paper is available. 

 

Academic Integrity:  “It is the responsibility of the student to refrain from infractions of academic integrity, from conduct that may lead to suspicion of such infractions, and from conduct that aids others in such infractions” Code of Policies and Regulations, Section 33.  All students are responsible for knowing the policies regarding academic integrity.  Suspected infractions of academic integrity will be addressed as mandated by the Code.

 

Special Needs:           Anyone with special needs should contact Drs. Kesler or Miller by January 23, 2004.

 

Text:   Senger, P.L.  2003.  Pathways to Pregnancy and Parturition (2nd edition ).  Pullman, WA:  Current Conceptions, Inc.

                This is an excellent text and is highly recommended.

 

Quizzes:        There are two types of quizzes:  in-class and on-line.

·       There are five in-class quizzes.  Four are scheduled and one is unannounced.  If you do not attend the class when the quiz is offered you will receive a zero; however, a make-up quiz will be offered on the last day of class.  The make-up quiz may be used to make-up one quiz that you missed or you may replace an existing lower score (hence allowing two drops).  This policy is firm—no exceptions. 

·       You are required to complete five on-line lecture quizzes.  The on-line lecture quizzes must be completed by noon on the designated day:  2/4, 2/25, 3/17, 4/14, and 4/28.  Details regarding the on-line quizzes will be provided at the first lab.

           

Lactation Exam:        The lactation exam will be an on-line exam.  This exam will be available online sometime on 5/3, but after lecture.  It must be completed by noon on 5/5 and is immediately graded.  This will allow you to know if you need to complete the comprehensive final.

 

Thinking Activities: These activities provide strategies for thinking at a higher level and will help you with the problem-solving and creative and critical thinking questions.  There will be five thinking activities that will used in the final grade (15 point each); however, addition thinking activities, that will not be used to calculate the final grade, will be included to improve thinking skills.

 

Examinations (Thinking Exercises), Review Sessions, and the Final:       Exams are thinking exercises.  Exams 1, 2, 3, and 4 will be given during the evening (7:30 P.M.).  This is to give you more time to complete the exam and to ensure that students may attend optional review sessions (the class on the day of the exam).  Having the exams in the evening will allow students the time to complete questions that require greater thought.  Therefore, exams will not be races against time.  You will have two full hours to complete the exam.

 

The exams will be in the following locations.

Exam #1

February 11

150 ASL

 

Exam #2

March 3

150 ASL

 

Exam #3

March 31

150 ASL

 

Exam #4

April 21

150 ASL

 

The comprehensive final examination (thinking exercise) is scheduled for May 12, 2004 at 8:00 A.M. in room 150 ASL.  One exam score, selected from the four lecture exams and the final, will be excluded from the final grade.  Therefore, if you are satisfied with your four lecture exam scores you need not take the comprehensive final.

 

Optional Paper:        This paper is worth 200 points and is added to the total points.  Therefore, with the optional paper your total points will be 1200.  The optional paper may improve your grade but will not lower your grade.  Papers will be graded based on quality–not quantity.  Papers must be based on several technical references.  Topics and references are due on 4/14.  A rough draft of the paper is due on 4/28 and the final draft is due 5/5 at 5:00 P.M.

 

Laboratory Section:  Dr. Miller is the lead instructor for the laboratory section of this class.  The URL for the laboratory syllabus is as follows:  http://www.ansci.uiuc.edu/classes/ansci231/lab.htm.

 

On-line Quizzes and Exams:          On-line quiz and exam questions use Mallard.  Details regarding the on-line questions will be provided at the first lab.  The Mallard site is as follows: https://mallard1.cites.uiuc.edu/ANSCI231/.

 

Supplementary Texts:

                Gilbert, Scott F.  2000.  Developmental Biology.  Suderland, MA:  Sinauer Associates, Inc.

                Hadley, Mac E.  2000.  Endocrinology.  Upper Saddle River, NJ:  Prentice Hall.

                Medical Economics Company.  2001.  Physicians’ Desk Reference (55 Edition).  Montvale, NJ:  Medical Economics Company, Inc.

                Veterinary Medicine Publishing Group.  1999.  Veterinary Pharmaceuticals and Biologicals.  Lenexa, KS:  Veterinary Medicine Publishing Group.

                Yu, Hing-Sing.  1994.  Human Reproductive Biology.  Boca Raton, FL:  CRC Press.

           

Journals:       Readings from various peer-reviewed journals, including but not limited to the following, will be used during the semester.

                Science

                Nature

                Journal of Animal Science

                Journal of Dairy Science

                Theriogenology

                Biology of Reproduction

                Animal Reproduction Science

 

Lecture Schedule

 

1.  Reproductive Anatomy, Systems, and Endocrinology

 

1/21

Introduction; History and Reproductive Variations

Kesler

1/23

Embryogenesis

Kesler

1/26

Female Reproductive Anatomy

Kesler

1/28

*Hypothalamus-Pituitary Axis

Kesler

1/30

Negative Feedback, Thyroid System, and Bioenergetics

Kesler

2/2

Growth Endocrinology

Kesler

2/4

+Hormone Chemistry, Synthesis, and Function

Kesler

2/6

Thinking Activity:  Pharmaceutical Dosing      Calculators Needed

Kesler

2/9

Hormone Chemistry, Synthesis, and Function

Kesler

2/11

Exam #1

 

 

2.  Reproductive Cycles:  Physiology and Control

 

2/13

Comparative Reproductive Cycles

Kesler

2/16

Follicular Phase and Folliculogenesis

Kesler

2/18

*Ovulation

Kesler

2/20

Luteal Phase and Luteolysis

Kesler

2/23

Luteolysis and Maternal Recognition of Pregnancy

Kesler

2/25

+Ovulation Inhibition and Control

Kesler

2/27

Ovulation Inhibition and Control

Kesler

3/1

Thinking Activity:  Reproductive Control

Kesler

3/3

Exam #2

 

 

3.  Male Reproduction, Gametes, and Fertilization

 

3/5

Male Reproductive Endocrinology

Kesler

3/8

Thinking Activity:  Androgen Therapy (research article)

Kesler

3/10

*Male Reproductive Anatomy

Miller

3/12

Sperm Anatomy and Spermatogenesis

Miller

3/15

Spermatogenesis and Male Reproductive Behavior

Miller

3/17

+Oocyte Maturation, Meiosis, and Genetic Recombination

Miller

3/19

Oocyte Maturation, Meiosis, and Genetic Recombination

Miller

3/29

Fertilization and Gamete Transport

Miller

3/31

Exam #3

 

 

4.  Pregnancy, Infertility, and Reproductive Technology

 

4/2

Pregnancy Detection/Diagnosis and Hormones of Pregnancy

Kesler

4/5

Early Embryo Development, Differentiation, & Mortality

Kesler

4/7

*Pregnancy, Pregnancy Loss, Fetal Development, and Placentation

Kesler

4/9

Parturition

Kesler

4/12

Puberty, Seasonal Anestrus, and Pineal Gland; Lactation/Postpartum Anestrus

Kesler

4/14

+Infectious and Noninfectious Reproductive Diseases and Dysfunctions

Kesler

4/16

Thinking Activity:  Infertility (problem-solving mysteries)

Kesler

4/19

Reproductive Technologies

Kesler

4/21

Exam #4

 

 

5.  Lactation Biology

 

4/23

Introduction to Lactation Biology

Hurley

4/26

Milk Composition and Synthesis

Hurley

4/28

+Mammary Gland Growth and Development

Hurley

4/30

Physiology of Lactation         

Hurley

5/3

Factors Affecting Milk Synthesis and Composition

Hurley

5/5

+Make-up Quiz and Thinking Activity

Kesler

5/12

Comprehensive Final Examination (8:00 A.M.–11:00 A.M; Wednesday)

 

 

* In-class lecture quiz; + On-line lecture quiz (must be completed by noon on designated day)



[1]It is important to maintain and use this syllabus throughout the semester.  More than 95% of the questions I receive about the course, other than content questions, are provided within the syllabus.  The URL is as follows:  http://www.ansci.uiuc.edu/classes/ansci231/index.htm.

 

[2]Dr. Kesler is the lead instructor for the lecture portion of the course.  Dr. Miller is the lead instructor for the laboratory portion of the course (details provided in laboratory).

[3]The lowest test, selected from first four exams and the comprehensive final, will be excluded from the final grade.

 

[4]Exams can be made up only if clearly valid excuses are presented in writing and approved.  In most cases this requires that you present your excuse before the exam.

 

[5]The comprehensive final will only include subject matter up to and including 4/21, 2004.

 

[6]The lowest quiz, selected from the in-class quizzes and make-up quiz, will be excluded from the final grade.  If you miss a class offering the quiz you will receive a zero; however, there is a make-up quiz offered at the last class.