Endocrine Modulators
Lactation Biology

For more on the Endocrine Modulators see:

Phytoestrogens

Adams NR   (1977) Morphological changes in the organs of ewes grazing oestrogenic subterranean clover. Res Vet Sci 22:216-221

Adams NR (1995) Detection of the effects of phytoestrogens on sheep and cattle. J Anim Sci 73:1509-1515

Akiyama, T., J. Ishida, S. Nakagawa, H. Ogawara, S. Watanabe, N. Itoh, M. Shibuya, and Y. Fukami.   1987.   Genistein, a specific inhibitor of tyrosine-specific kinases.   J. Biol. Chem. 5592-5595.

Brown NM, Lamartiniere CA (1995) Xenoestrogens alter mammary gland differentiation and cell proliferation in the rat. Environ Health Perspect 103:708-713

Chemopreventative Branch and Agent Development Committee, NCI, DCPC (1997) Clinical development plan: genistein. J Cell Biochem 265:114-126

Drane HM, Wrathall AE, Patterson, DSP, Hebert CN (1981) Possible oestrogenic effects of feeding soymeal to prepubertal gilts. Br Vet J 137:283-288

Eldridge-White R, Easter RA, Heaton DM, O'Day MB, Petersen GC, Shanks RD, Tarbell MK, Sherwood OD (19898) Hormonal control of the cervix in pregnant gilts. I. Changes in the physical properties of the cervix correlate temporally with elevated serum levels of estrogen and relaxin. Endocrinology 125:2996-3003

Fan, G. and J. A. Rillema.   1992.   Effect of tyrosine kinase inhibitor, genistein, on the actions of prolactin in cultured mouse mammary tissues.   Mol. Cell. Endocrinol. 83:51-55

Imagawa W, Yang J, Guzman R, Nandi S (1994) Control of mammary gland development. Ch. 56 in The Physiology of Reproduction , 2 nd Ed., ed E Knobil and JD Neill, Raven Press, NY

Kaldas RS, Hughes, Jr, CL (1989) Reproductive and general metabolic effects of phytoestrogens in mammals. Reprod Tox 3:81-89

Lamartiniere CA, Moore JB, Brown NM, Thompson R, Hardin MJ, Barnes S (1995) genistein suppresses mammary cancer in rats. Carcinogenesis 16:2833-2840

Liu K-S (1997) Soybeans: Chemistry, Technology, and Utilization . Chapman and Hall, New York, NY

Lundh T (1995) Metabolism of estrogenic isoflavones in domestic animals. Proc Soc Exp Biol Med 208:33-339

Murrill WB, Brown NM, Zhang J-X, Manzolillo PA, Barnes S, Lamartiniere CA (1996) Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats.   Carcinogenesis 17:1451-1457

Santell RC, Chang YC, Nair MG, Helferich WG. (1997) Dietary genistein exerts estrogenic effects upon the uterus, mammary gland and the hypothalamic/pituitary axis in rats. J Nutr 127:263-269

Suttner A, Danilovich NA, Banz WJ, Winters TA (1998) The effects of the phytoestrogen daidzein on in situ apoptosis in primary porcine granulosa cells. Biol Reprod 58(Suppl 1):74

Verdeal, K., R. B. Brown, T. Richardson, and D. S. Ryan.   Affinity of phytoestrogens for estradiol-binding proteins and effect of coumestrol on growth of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.   J. Natl. Cancer Inst. 64:285-290.

Wang, W., Y. Tanaka, Z. han, and C. M. Higuchi.   1995.   Proliferative response of mammary glandular tissue to formononetin.   Nutr. Cancer 23:131-140

Whitten PL, Lewis C, Naftolin F (1993) A phytoestrogen induces the premature anovulatory syndrome in lactationally exposed female rats. Biol Reprod 49:1117-1121 Whitten PL, Russell E, Naftolin F (1992) Effects of a normal, human-concentration, phytoestrogen diet on rat uterine growth. Steroids 57:98-106